Bi-specific T-cell engager antibodies (BiTEs) are synthetic fusion molecules that combine multiple antibody-binding domains to induce active contact between T-cells and antigen expressing cells in the LED Globe body.Blinatumomab, a CD19-CD3 BiTE is now a widely used therapy for relapsed B-cell malignancies, and similar BiTE therapeutics have shown
Purpose: to characterize from the position of a systematic approach the problems of applying legislation in the field of physical culture and sports in modern conditions of functioning and to propose ways to solve them.Material and methods: to solve the set research tasks, a set of theoretical LED Globe methods was used: analysis, comparison, gener
Molecular confirmation of the process of differentiation of meristematic tissue of plants is primarily based on histomorphological characterization of the tissues carrying these processes.For perennial plants - fruit trees, the knowledge of these processes is important to define runtime type and pomotechnical treatments but also to identify the gen
The Stationery article deals with the genesis, semantics, and functions of the dragon image in Japanese culture.The relevance of the study is due to the increased attention of researchers to the basic values of local cultures, issues of symbolism, inextricably linked to the problems of national self-identification.The methodological basis of the st
Automatic pancreas segmentation of CT scans enables physicians to identify and monitor the abnormalities in the pancreas.This facilitates intraoperative assistance, surgical planning, prognosis, and diagnosis.Nonetheless, the size and location of the pancreas in the CT image input data present a significant challenge for automatic segmentation, and